Increased expression of microRNA-21 in peripheral blood mediates the down-regulation of IFN-γ and increases the prevalence of stroke-associated infection

Increasing levels of microRNA (miRNA)-21 can lead to IFN-γ deficiency, thereby suppressing immune function. Whether changes in the peripheral blood expression of miRNA-21 in patients with acute stroke are related to stroke-associated infection (SAI) remains unsettled.

Source: Journal of the Neurological Sciences - April 4, 2016 Category: Neurology Authors: Shao-Peng Lin, Shan Ye, Xiao-Hui Chen, Hui-Lin Jiang, Hai-Feng Mao, Mei-Ting Chen, Qiu-Jie Ma, Youming Long, Yongxiang Fan, Pei-Yi Lin Source Type: research