Smoking and RA: A Deadly Combination (CME/CE)

(MedPage Today) -- Medium-term mortality doubled in smokers with rheumatoid arthritis
Source: MedPage Today Geriatrics - Category: Geriatrics Source Type: news

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Analyst, 2019, Accepted Manuscript DOI: 10.1039/C8AN02014K, PaperDehui Sun, Fanlei Hu, Huanyu Gao, Zhijing Song, Wenchun Xie, Ping Wang, Lianjie Shi, Ke Wang, Yan Li, Chuncui Huang, Zhanguo Li Glycosylation is a post-translational modification essential for maintaining the structure and function of proteins. Abnormal N-glycan patterns have been found in various diseases compared to healthy controls. Decrease in terminal... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
Introduction: Despite the availability of multiple pharmaceutical and targeted biological drugs for treatment of rheumatoid arthritis (RA), many patients exhibit intolerability or inadequate clinical response. Modulating innate anti-inflammatory neuro-immune pathways through electrical stimulation of the vagus nerve may represent a novel, nonpharmacological means of treating RA and other immune-mediated inflammatory diseases. We recently reported a 12-week proof-of-concept study with an implanted neuromodulation device, showing reduction in the DAS28-CRP disease activity score, with concomitant reductions in TNF - α ...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research
BACKGROUND: Rheumatoid arthritis patients may have an increased risk of falls due to changes caused by the disease such as muscle weakness, joint impairment, reduced mobility and postural instability. The aim of this study was to prospectively analyze the ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
ConclusionDiscontinuing a TNFi before gestational week 20 seems feasible in women with RA and JIA who enter pregnancy with well ‐controlled disease.This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Full Length Source Type: research
ConclusionsIn RA clinical trials, no association was found between baricitinib treatment and MACE, ATE, or CHF. For DVT/PE, 6 events were reported for baricitinib 4 ‐mg but not placebo; during longer‐term evaluation, IRs were similar between doses, consistent over time, and similar to published rates in RA.This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Full Length Source Type: research
ConclusionPersistence varied widely depending on the definition of discontinuation, with the majority of nonpersistent patients restarting biological therapy shortly after discontinuation.
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research
Expression of T follicular helper lymphocytes with different subsets and analysis of serum IL-6, IL-17, TGF-β and MMP-3 contents in patients with rheumatoid arthritis. Eur Rev Med Pharmacol Sci. 2019 Jan;23(1):61-69 Authors: Sun WK, Bai Y, Yi MM, Wu LJ, Chen JL, Wu DM, Wu HW, Wan L, Meng Y, Zhang QL Abstract OBJECTIVE: To investigate the expression levels of T follicular helper (Tfh) with different subsets in patients with rheumatoid arthritis (RA) and their serum interleukin-6 (IL-6), interleukin-17 (IL-17), transforming growth factor-β (TGF-β) and matrix metalloproteinase 3 (MMP-3) con...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Authors: Li GH, Ren DH, Yu S, Chen J, Fang K, Li ZH, Cai L, Shi ZL, Zhang JY, Ma JI Abstract Non-adherence in patients with rheumatoid arthritis (RA) using disease-modifying antirheumatic drugs (DMARDs) may lead to increased disease activity and symptoms, poorer quality of life and increased costs related to the disease treatment. The aim of this study is to determine the level of adherence to the treatment protocols of a chronic disease such as rheumatoid arthritis in the Albanian population and to investigate the predictors of adherence to medication. This is a single-center cross-sectional study in which include...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
Authors: Këlliçi S, Mihani J, Miraçi M, Fida M, Backa T Abstract Non-adherence in patients with rheumatoid arthritis (RA) using disease-modifying antirheumatic drugs (DMARDs) may lead to increased disease activity and symptoms, poorer quality of life and increased costs related to the disease treatment. The aim of this study is to determine the level of adherence to the treatment protocols of a chronic disease such as rheumatoid arthritis in the Albanian population and to investigate the predictors of adherence to medication. This is a single-center cross-sectional study in which included 125 pat...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
Authors: Kotyla PJ Abstract PMID: 30652676 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
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