My personal USMLE Problem( yes I think i am queen :p)- Biochem Thread

Hey guys,

So i have stated a biochem thread please bear out with me.

I came across this note:
In all, translation uses 4 high-energy phosphate bonds per amino acid:

2 during aminoacylation (tRNA charging): ATP → AMP (A for Activation)
1 during tRNA "loading" into the A-site: GTP → GDP (G for Gripping)
1 during translocation: GTP → GDP (G for Going places)
I just wanna know why 2 during amionoacylation. Isn't it just one bond bcs ATP is broken to AMP and PPi?
I...

My personal USMLE Problem( yes I think i am queen )- Biochem Thread

Source: Student Doctor Network - March 26, 2016 Category: Universities & Medical Training Authors: HarveyR Source Type: forums