Serotonin disrupts esophageal mucosal integrity: an investigation using a stratified squamous epithelial model

Conclusions Serotonin disrupted esophageal squamous epithelial barrier function by modulating the levels of TJ proteins. Serotonin signaling pathways may mediate the pathogenesis of gastroesophageal reflux disease.
Source: Journal of Gastroenterology - Category: Gastroenterology Source Type: research