Hemangiomas recur in 25% of infants after propranolol stopped

Infantile hemangiomas treated with propranolol recurred in 25% of children after discontinuation of propranolol in a retrospective study of nearly 1,000 patients, according to findings published...
Source: Pediatric News - Category: Journals (General) Source Type: news

Related Links:

ConclusionThis study evidences that silence of lncRNA UCA1 inhibits hemangioma cells growth, migration and invasion possibly via its regulation on miR-200c expression and the activation of mTOR, AMPK and Wnt/β-catenin signaling pathways.
Source: Life Sciences - Category: Biology Source Type: research
We report a unique case of epithelioid hemangioma with multifocal metachronous bone lesions without any fatal outcome observed after a long period. Importantly, a strong nuclear expression of FOSB antibody was detected by immunohistochemical analysis. In this case, the pathologic and radiologic findings are also described. We suggest that epithelioid hemangioma can present multifocal metachronous bone lesions without producing a fatal outcome.
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
AbstractObjectiveTo comprehensively assess precision, reproducibility, and repeatability of iodine maps from spectral detector CT (SDCT) in a phantom and in patients with repetitive examination of the abdomen.MethodsSeventy-seven patients who underwent examination two (n = 52) or three (n = 25) times according to clinical indications were included in this IRB-approved, retrospective study. The anthropomorphic liver phantom and all patients were scanned with a standardized protocol (SSDE in patients 15.8 mGy). In patients, i.v. contrast was administered and portal venous images were acquired...
Source: European Radiology - Category: Radiology Source Type: research
Authors: Zhang K, Wang F, Huang J, Lou Y, Xie J, Li H, Cao D, Huang X Abstract Infantile hemangioma (IH), which is the most common tumor in infants, is characterized by rapid proliferation followed by spontaneous regression into fibro-fatty tissue in childhood. However, its specific mechanism has not been clarified. Our previous studies showed that insulin-like growth factor 2 (IGF-2) is increased in the proliferative phase of IH, which is deemed to form from hemangioma-derived stem cells (HemSC). However, it remains unclear whether IGF-2 can promote the adipogenic differentiation of HemSCs and the signaling mechan...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Pulmonary Hypertension (PH) is classified into distinct phenotypic groups1 and patients with pulmonary arterial hypertension (PAH) belong to group 1 in the classification scheme. Pulmonary veno-occlusive disease (PVOD) and pulmonary capillary hemangiomatosis belong to group 1 ’, PH associated with lung diseases and/or hypoxemia are classified into group 3, and chronic thromboembolic PH (CTEPH) into group 4 1. The incidence of detection of cancer after diagnosis of precapillary PH is unknown and such patients may be exposed to several carcinogens (smoking, alcohol, occu pational exposure).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Conclusion The dynamic analysis of tumor contrast enhancement with the TurboFLASH sequence provides useful additional information to that obtained with conventional MR, improving the differential diagnosis of skull base tumors, particularly in the distinction between glomus and nonglomus tumors and in diagnosing CSCH. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Journal of Neurological Surgery Part B: Skull Base - Category: Neurosurgery Authors: Tags: Original Article Source Type: research
A lesion on a patient's heel is confirmed to be a verrucous hemangioma. Find out how this case was identified, diagnosed, and successfully treated.ePlasty, Open Access Journal of Plastic Surgery
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Plastic Surgery & Aesthetic Medicine Journal Article Source Type: news
We present the case of a 6-year-old girl followed since birth for PHACE syndrome and left hemifacial haemangioma, who presented with left hearing loss. Computed tomography scan showed left persistent stapedial artery (PSA).DiscussionTwo types of arterial anomalies may be observed in PHACE syndrome: persistence of embryonic arteries and anomalies of cerebral arteries. PSA can be observed in the context of PHACE syndrome. Children with PHACE syndrome require regular audiometric follow-up to detect hearing loss and avoid its consequences on speech and language development.
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - Category: ENT & OMF Source Type: research
Conclusion Our results confirm that mutations are found in genes beyond BMPR2 in heritable PAH, emphasise the role of TBX4 and BMP9, and designate BMP10 as a new PAH gene.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Pulmonary vascular disease Original Articles: Pulmonary vascular disease Source Type: research
AbstractPrimary cardiac neoplasms are rare, cardiac hemangiomas are even rarer, and a mixed thrombus followed by a primary cardiac hemangioma is exceptionally rare epidemiology. Here, we report the case of a man with a right atrium mixed ‐thrombus surgical history who went on to develop a cardiac hemangioma.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: CASE REPORT Source Type: research
More News: Children | General Medicine | Hemangioma | Inderal | Pediatrics | Study