The association of circulating angiogenic factors and HbA1c with the risk of preeclampsia in women with preexisting diabetes.

CONCLUSIONS: Women with diabetes had a markedly altered anti-angiogenic state late in pregnancy that was further exacerbated in subjects who developed PE. Altered angiogenic factors may be one mechanism for the increased risk of PE in this population. Increased HbA1c in the first trimester of pregnancies in women with diabetes was strongly associated with subsequent PE. PMID: 24354578 [PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/24354578?dopt=Abstract

Source: Hypertension in Pregnancy - February 17, 2016 Category: OBGYN Tags: Hypertens Pregnancy Source Type: research