Applications of platelet-rich plasma in dermatology: A critical appraisal of the literature.

Applications of platelet-rich plasma in dermatology: A critical appraisal of the literature.
J Dermatolog Treat. 2015 Oct 14;:1-5
Authors: Lynch MD, Bashir S
Abstract
Platelet-rich plasma (PRP) is an autologous blood-derived product enriched in platelets, growth factors, chemokines and cytokines. Initial applications were predominantly in musculoskeletal and maxillofacial fields, however in recent years, it has been used for a range of dermatological indications including wound healing, fat grafting, alopecia, scar revision and dermal volume augmentation. Here, we critically appraise the literature relating to the usage of PRP within Dermatology. We have evaluated in vitro data, preclinical animal studies and human trials. We conclude that, whilst the literature may be consistent with a modest benefit for specific indications, there is not sufficient evidence supporting the efficacy of PRP to justify a role in routine dermatological practice at the present time. However, since PRP is generally well tolerated with few reported complications, further study may be justified in the context of organized trials.
PMID: 26466811 [PubMed - as supplied by publisher]

Source: Journal of Dermatological Treatment - February 16, 2016 Category: Dermatology Tags: J Dermatolog Treat Source Type: research