Chimeric antigen receptor (CAR)-engineered T cells redirected against hepatitis C virus (HCV) E2 glycoprotein

Conclusions
Clearance of HCV-infected cells is a major therapeutic goal in chronic HCV infection, and adoptive transfer of anti-HCV/E2 CARs-grafted T cells represents a promising new therapeutic tool.

Source: Gut - February 12, 2016 Category: Gastroenterology Authors: Sautto, G. A., Wisskirchen, K., Clementi, N., Castelli, M., Diotti, R. A., Graf, J., Clementi, M., Burioni, R., Protzer, U., Mancini, N. Tags: Open access Hepatology Source Type: research