Proteus syndrome: evaluation of the immunological profile

We report on the novel immunologic findings of a 15 years old girl affected with PS. Detailed T and B cell evaluation revealed maturational alterations for both subsets and functional hyperactivation for the latter. Such findings have not been reported previously in PS and may be the spy of more complex immune abnormalities in this syndrome.

Source: Orphanet Journal of Rare Diseases - January 13, 2016 Category: Internal Medicine Authors: Vassilios LougarisVincenzo SalpietroMaricia CutrupiManuela BaronioDaniele MorattoM. PizzinoKshitij MankadSilvana BriugliaCarmelo SalpietroAlessandro Plebani Source Type: research