Expression and function of histamine and its receptors in atopic dermatitis

Conclusions With this review, we provide an overview on histamine and the expression of its four receptors on skin resident and nonresident cells. Furthermore, we summarize recent studies which suggest anti-histamine therapy to efficiently combat pruritus and inflammation in atopic dermatitis and discuss possible approaches to incorporate these findings into more effective treatment strategies for atopic dermatitis in childhood.
Source: Molecular and Cellular Pediatrics - Category: Cytology Source Type: research