What are the most reliable signs for the radiologic diagnosis of uterine adenomyosis? An ultrasound and MRI prospective

Conclusions MRI is superior to sonography in the diagnosis of uterine adenomyosis though we still recommend to start with the latter owing to its availability.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - Category: Nuclear Medicine Source Type: research

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Publication date: Available online 2 January 2020Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): A. Gentry-Maharaj, C. KarpinskyjAbstractDue largely to the rise in obesity and prolonged life expectancy, endometrial cancer rates have increased by 56% since the early 90s. Women at high risk (Lynch Syndrome) have a 12-47% lifetime risk of developing endometrial cancer and professional societies recommend annual surveillance using transvaginal ultrasound (TVS) and endometrial biopsy (outpatients hysteroscopy) from age 30-35 with hysterectomy from age 40. In women at low risk, screening is not...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
ConclusionWhilst radical completion surgery should be advised in UA, this case, in addition to all published conservatively managed cases of UA, demonstrates that conservative management is possible in appropriately selected women. Intensive monitoring post-operatively is essential owing to the risk of recurrence; however, this may pose deleterious side effects which require consideration.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
ConclusionDue to the heterogeneity of the tissue sampling techniques, diverse patient populations, and significant conflicting recommendations, no conclusive recommendation on the optimal tissue sampling technique can be made. However, it is of the authors opinion that it would be reasonable to limit uterine tissue sampling for confirmatory diagnosis of adenomyosis in those patients with a suspicion of adenomyosis based on both symptom profile and pelvic ultrasound, where a planned diagnostic laparoscopy for either infertility or pelvic pain has already been contemplated and scheduled, and where the confirmatory results ma...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
AbstractAdenomyosis is a challenging clinical condition that is commonly being diagnosed in women of reproductive age. To date, many aspects of the disease have not been fully understood, making management increasingly difficult. Over time, minimally invasive diagnostic and treatment methods have developed as more women desire uterine preservation for future fertility or to avoid major surgery. Several uterine-sparing treatment options are now available, including medication, hysteroscopic resection or ablation, conservative surgical methods, and high-intensity focused ultrasound each with its own risks and benefits. Uteri...
Source: Insights into Imaging - Category: Radiology Source Type: research
We report a case of misdiagnosed endometrial cancer by D&C, but with a positive cytopathological finding. Following that, a meta-analysis including 4,179 patients of endometrial diseases with cyto-histopathological results was performed to assess the value of the endometrial cytological method in endometrial cancer diagnosis. The pooled sensitivity and specificity of the cytological method in detecting endometrial atypical hyperplasia or cancer was 0.91[95% confidence interval (CI) 0.74–0.97] and 0.96 (95% CI 0.90–0.99), respectively. The pooled positive likelihood ratio and negative likelihood ratio was 25.4 (...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Vit Weinberger1, Marketa Bednarikova2, Jitka Hausnerova3, Petra Ovesna4, Petra Vinklerova1, Lubos Minar1, Michal Felsinger1, Eva Jandakova3, Marta Cihalova3 and Michal Zikan5* 1Department of Gynecology and Obstetrics, University Hospital in Brno and Masaryk University, Brno, Czechia2Department of Internal Medicine – Hematology and Oncology, University Hospital in Brno and Masaryk University, Brno, Czechia3Department of Pathology, University Hospital in Brno and Masaryk University, Brno, Czechia4Faculty of Medicine, Institute of Biostatistics and Analyses, Masaryk University, Brno, Czechia5Institute of Biostati...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
A long-term retrospective study of patients treated with Gynesonics’ Sonata uterine fibroid treatment system revealed low rates of surgical reintervention, improved symptom severity and quality of life, the company said today. Patients at the study site in Monterrey, Mexico were treated with the Sonata system, designed to provide incisionless transcervical radiofrequency energy ablation of uterine fibroids under intrauterine ultrasound guidance. The mean follow-up period for the patients enrolled was 5.4 years. Highlights from the study include: No surgical reinterventions in the first 3.4 years. Annualized surgical...
Source: Mass Device - Category: Medical Devices Authors: Tags: Blog Clinical Trials Gynecological Imaging News Well Ultrasound Women's Health FDA Gynesonics Source Type: news
ConclusionObtaining additional tissue by routine curettage before endometrial ablation and/or endomyometrial resection, in conjunction with removal of any intrauterine lesions, can identify rare unexpected endometrial lesions not sampled by endometrial biopsy, not detected with ultrasound, and masquerading as leiomyomas during endometrial ablation.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
CONCLUSION: A GnRH agonist in combination with transient aromatase inhibitor and tranexamic acid is an effective management strategy to treat and maintain reproduction in women with AVMs associated with AUB. PMID: 30413336 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
Rationale: Placental site trophoblastic tumor (PSTT) is a very rare malignant tumor, belonging to a family of pregnancy-related illnesses, called gestational trophoblastic diseases (GTD). Less than 300 cases of PSTT have been reported in literature, with an incidence of ≈ 1/50,000–100,000 pregnancies representing only 0.23% to 3.00% of all GTDs. Patient concerns: Our report describes 2 additional cases of PSTT outlining their main diagnostic features and the subsequent management. The first case presented contemporary to a persistent hydatidiform mole in a 37-year-old woman, para 2042; whereas the second...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
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