Nuclear Localization of β-Catenin in Sertoli Cell Tumors and Other Sex Cord–Stromal Tumors of the Testis: An Immunohistochemical Study of 87 Cases

In conclusion, SCT-NOS and SSCT frequently show β-catenin nuclear localization. Positive nuclear staining of β-catenin is specific for SCT-NOS, SSCT, and Sertoli–stromal cell tumor among testicular sex cord–stromal tumors but has limited sensitivity (63%) in this group. The similar reactivity of SCT-NOS and SSCT provides additional support that these 2 variants are not distinct entities.
Source: The American Journal of Surgical Pathology - Category: Pathology Tags: Original Articles Source Type: research