Bariatric surgery, stomas and other digestive tract reductions: Insufficient data and recommendations to adapt medicines regimens in therapeutic practice.

[Bariatric surgery, stomas and other digestive tract reductions: Insufficient data and recommendations to adapt medicines regimens in therapeutic practice]. Presse Med. 2015 Sep 7; Authors: Bernard É, Charpiat B, Mabrut JY, Dode X, Garcia S, Le Duff M, Rose FX, Ducerf C Abstract Surgery modifying digestive tract may alter drugs pharmacokinetics. To maintain concentrations of active substance in their therapeutic ranges, a dosage adjustment or change of drug may be necessary. This is particularly important when no pharmacological or pharmacodynamic parameter reflecting the medication effectiveness is easily measurable. Our objective was to gather the information and documentary tools that can guide prescription in these patients with rearranged digestive tract. We searched information on the documentary portals of French agencies, on gray literature, on MEDLINE and in the summaries product characteristics. No information was found on the website of French agencies, sparse data were identified in gray literature. Some document are discordant, most are imprecise. One hundred and ten studies or case reports referenced on MEDLINE describe 79 medications pharmacokinetics after gastrointestinal surgery. Four are not available in France. Six literature reviews were found. Four summaries of product characteristics provided information related to drug absorption. No documentary tool adapted to clinical routine exists. This unsatisfactory situation is a barr...
Source: Presse Medicale - Category: Journals (General) Authors: Tags: Presse Med Source Type: research

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Conditions:   Obesity;   Postoperative Pain;   Bariatric Surgery Interventions:   Procedure: ESPB group;   Procedure: Control group Sponsor:   Antalya Training and Research Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
FRIDAY, Dec. 6, 2019 -- Individuals who undergo bariatric surgery may be at increased risk for developing colon cancer years later, according to a study published online Dec. 4 in the International Journal of Cancer. Wenjing Tao, from the Karolinska...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Women who had bariatric surgery between their first and second pregnancies had better pregnancy and birth outcomes, a study found.Medscape Medical News
Source: Medscape Diabetes Headlines - Category: Endocrinology Tags: Ob/Gyn & Women ' s Health News Source Type: news
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Source: British Journal of Neurosurgery - Category: Neurosurgery Authors: Source Type: research
This study aims to determine if cosmetic outcomes play an important role for patients undergoing bariatric surgery, when considering a surgical approach. A video-animation describing open, conventional laparoscopic, and reduced incision magnetic assisted surgery was shown. The patient ’s perceptions of the surgical approaches were recorded using an anonymous survey. Fifty-one patients completed the survey. The median age was 45 (IQR: 36–51), and 38 (74.5%) were women. Cosmesis was found to be an important factor (77%) for selecting a surgical approach. Ninety percent of the p atients believe that reduced incisi...
Source: Obesity Surgery - Category: Surgery Source Type: research
Authors: Üstün I, Solmaz A, Gülçiçek OB, Kara S, Albayrak R Abstract OBJECTIVES: Bariatric surgery is an effective intervention for severe obesity and associated comorbidities. We compared symptoms, joint space and life quality of morbidly obese patients with symptomatic knee osteoarthritis before and after bariatric surgery. METHODS: 34 patients with knee osteoarthritis were evaluated with standing anteroposterior and lateral radiography, medial and lateral joint distances of the knees, Visual Analog Scale (VAS), Western Ontario and McMaster Universities Arthritis Index (WOMAC) que...
Source: Journal of Musculoskeletal Neuronal Interactions - Category: Neurology Tags: J Musculoskelet Neuronal Interact Source Type: research
ConclusionsRYGB is an effective therapy for patients with BE and reflux after SG. Its outcomes in the current study were BE remission in the majority of cases as well as a decrease in reflux activity. Further studies with larger cohorts are necessary to confirm these findings.
Source: Obesity Surgery - Category: Surgery Source Type: research
Conclusion section should read as follows.
Source: Obesity Surgery - Category: Surgery Source Type: research
In Table 7 the following corrections are required.
Source: Obesity Surgery - Category: Surgery Source Type: research
ConclusionsDespite most patients having leftover opioids following surgery, few patients recognized possible overprescription. Education regarding opioid use following surgery is inconsistent, potentially contributing to the amount of retained opioids currently available. Future guidelines should focus on determining the appropriate amount of opioids to be prescribed following surgery and standardizing and improving education given to patients.
Source: Obesity Surgery - Category: Surgery Source Type: research
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