Betulinic acid exerts anti‐hepatitis C virus activity via the suppression of NF‐κB‐ and MAPK‐ERK1/2‐mediated COX‐2 expression

Conclusions and ImplicationsBA inhibits HCV replication by suppressing the NF‐κB‐ and ERK1/2‐mediated COX‐2 pathway and may serve as a promising compound for drug development or as a potential supplement for use in the treatment of HCV‐infected patients.

Source: British Journal of Pharmacology - August 3, 2015 Category: Drugs & Pharmacology Authors: Chun‐Kuang Lin, Chin‐Kai Tseng, Kai‐Hsun Chen, Shih‐Hsiung Wu, Chih‐Chuang Liaw, Jin‐Ching Lee Tags: RESEARCH PAPER Source Type: research