[Nalbuphine in pediatric anesthesia.]

[Nalbuphine in pediatric anesthesia.]
Anaesthesist. 2014 Feb 7;
Authors: Schultz-Machata AM, Becke K, Weiss M
Abstract
Efficient and safe pediatric perioperative pain therapy in the context of a multimodal pain therapy concept requires a slight to moderate opioid analgesic. Nalbuphine is a nearly ideal opioid for this purpose due to its unique pharmacological properties as a μ-receptor antagonist/κ-receptor agonist and a high safety profile. Nalbuphine is used clinically primarily in postoperative pain therapy administered as a bolus, continuous infusion and patient-controlled analgesia. Furthermore, it is administered in different regimens for pediatric diagnostic and interventional sedation.
PMID: 24504192 [PubMed - as supplied by publisher]

Source: Der Anaesthesist - February 7, 2014 Category: Anesthesiology Authors: Schultz-Machata AM, Becke K, Weiss M Tags: Anaesthesist Source Type: research