Lipopeptide surfactants: Production, Recovery and Pore Forming Capacity

Publication date: Available online 17 July 2015 Source:Peptides Author(s): Mnif Inès, Ghribi Dhouha Lipopeptides are microbial surface active compounds produced by a wide variety of bacteria, fungi and yeast. They are characterized by highly structural diversity and have the ability to decrease the surface and interfacial tension at the surface and interface, respectively. Surfactin, Iturin and Fengycin of Bacillus subtilis are among the most studied lipopeptides. This review will present the main factors encountering lipopeptides production along with the techniques developed for their extraction and purification. Moreover, we will discuss their ability to form pores and destabilize biological membrane permiting their use as antimicrobial, hemolytic and antitumor agents. These open great potential applications in biomediacal, pharmaceutic and agriculture fields.

Source: Peptides - July 18, 2015 Category: Biochemistry Source Type: research