E3 ubiquitin ligase RNF128 negatively regulates the IL-3/STAT5 signaling pathway by facilitating K27-linked polyubiquitination of IL-3R α

IL-3/STAT5 signaling pathway is crucial for the development and activation of immune cells, contributing to the cellular response to infections and inflammatory stimuli. Dysregulation of the IL-3/STAT5 signali...

Source: Cell Communication and Signaling - May 3, 2024 Category: Molecular Biology Authors: Jingge Yu, Jianguo Li, Ao Shen, Zhiping Liu and Tian-Sheng He Tags: Research Source Type: research