Gram-scale approach for β-costic acid via allylic oxidation of β-selinene

Biosci Biotechnol Biochem. 2024 May 1:zbae052. doi: 10.1093/bbb/zbae052. Online ahead of print.ABSTRACTβ-Costic acid is a sesquiterpene phytoalexin with acaricidal activity against Varroa destructor and antitrypanosomal activity. A concise and efficient method was developed for the synthesis of β-costic acid via the allylic oxidation of β-selinene, a component of celery seed oil.PMID:38692843 | DOI:10.1093/bbb/zbae052
Source: Bioscience, Biotechnology, and Biochemistry - Category: Biochemistry Authors: Source Type: research