Plasmablastic myeloma transformation of light-chain multiple myeloma

J Clin Exp Hematop. 2024 Apr 30. doi: 10.3960/jslrt.24004. Online ahead of print.ABSTRACTPlasmablastic myeloma (PBM) is an uncommon and aggressive morphologic variant of multiple myeloma (MM). The neoplastic immature cells exhibit diverse morphology, posing a diagnostic challenge. The diagnostic criteria for PBM include the identification of ≥ 2% plasmablasts in the bone marrow aspirate. This case describes the incidental finding of a light-chain multiple myeloma (LCMM) transformed into PBM, a phenomenon not previously reported.PMID:38684404 | DOI:10.3960/jslrt.24004

Source: Journal of Clinical and Experimental Hematopathology : JCEH - April 29, 2024 Category: Hematology Authors: Nagehan Pakasticali Glen L Hortin Julie Y Li Source Type: research