Leukopenia, neutropenia, and procalcitonin levels in young febrile infants with invasive bacterial infections

CONCLUSIONS: Leukopenia ≤2500 cells/μL in febrile infants ≤60 days old is associated with IBIs. However, in the presence of normal PCT levels, no patients with leukopenia had IBIs. While this suggests leukopenia ≤2500 cells/μL is a risk factor for IBIs in non-critically ill young febrile infants only when PCT is unavailable or elevated, the overall low frequency of leukopenia in this cohort warrants caution in interpretation, with future validation required.PMID:38661246 | DOI:10.1111/acem.14921

Source: Accident and Emergency Nursing - April 25, 2024 Category: Emergency Medicine Authors: Andrew T Krack Michelle Eckerle Prashant Mahajan Octavio Ramilo John M VanBuren Russell K Banks T Charles Casper David Schnadower Nathan Kuppermann Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN) Source Type: research