An NIR-II-emitting type-I photosensitizer for efficient hypoxic tumor phototheranostics

Chem Commun (Camb). 2024 Apr 26. doi: 10.1039/d4cc00431k. Online ahead of print.ABSTRACTA small molecule-based NIR-II type-I photosensitizer (IT-IC) with a strong push-pull effect and good planar π-conjugated structure was synthesized. The IT-IC NPs exhibited strong light absorption, outstanding NIR-II fluorescence emission, excellent photothermal conversion and efficient type-I/II ROS generation, showing encouraging therapeutic outcomes for hypoxic tumors.PMID:38666540 | DOI:10.1039/d4cc00431k

Source: Chemical Communications - April 26, 2024 Category: Chemistry Authors: Qi Wang Ruoqing Wang Xiaoyuan Wang Mingxuan Fu Yicong Gao Jianfeng Feng Renyong Geng Zhen Yuan Quli Fan Feng Lu Source Type: research