Single-cell analysis reveals context-dependent, cell-level selection of mtDNA

Nature, Published online: 24 April 2024; doi:10.1038/s41586-024-07332-0A new method for tracking single-cell heteroplasmy, called SCI-LITE, is combined with mitochondrial DNA base editing to reveal principles of heteroplasmy dynamics in dividing cells.

Source: Nature AOP - April 24, 2024 Category: Research Authors: Anna V. Kotrys Timothy J. Durham Xiaoyan A. Guo Venkata R. Vantaku Sareh Parangi Vamsi K. Mootha Source Type: research