Ten cyclopentanoid monoterpenes from the whole plant of Rehmannia piasezkii maxim

Fitoterapia. 2024 Apr 16;175:105968. doi: 10.1016/j.fitote.2024.105968. Online ahead of print.ABSTRACTTen new cyclopentanoid monoterpenes (1-10) were isolated from the whole plant of Rehmannia piasezkii. The structures of these compounds were elucidated based on spectroscopic data analysis. In in-vitro assays, compounds 3, 7, and 9 exhibited weak hepatoprotective activities against APAP-induced HepG2 cell damage. Compound 9 exhibited protective effect on hapassocin carbon tetrachloride model.PMID:38636908 | DOI:10.1016/j.fitote.2024.105968

Source: Fitoterapia - April 18, 2024 Category: Biochemistry Authors: Jie Zhou Guoru Shi Wanqi Zhang Ruoyun Chen Shishan Yu Dequan Yu Yanfei Liu Source Type: research