Construction of thioglycoside bonds via an asymmetric organocatalyzed sulfa-Michael/aldol reaction: access to 4 ′-thionucleosides

Chem. Commun., 2024, Advance Article DOI: 10.1039/D4CC00984C, CommunicationTao Wei, Ming-Sheng Xie, Hai-Ming Guo The construction of S –C–N glycosidic bondsvia the organocatalytic sulfa-Michael/aldol reaction of (E)- β-nucleobase acrylketone and 1,4-dithiane-2,5-diol was achieved, and diverse 4′-thionucleosides were obtained with excellent results. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Chem. Commun. latest articles - April 19, 2024 Category: Chemistry Authors: Tao Wei Source Type: research