GSE230710 GATAD2B containing NuRD complex drives R-loop dependent chromatin boundary formation at double strand breaks

Contributors : Zhichao Liu ; Kamal Ajit ; Monika GullerovaSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensTo understand how components of NuRD could be recruited to DNA double-stranded break sites, we generate site-specific DNA double strand breaks through an inducible endonuclease AsiSI-ER system by adding 4-OHT, we applied antibodies against GATAD2B and HDAC1, both of which are components of NuRD complex, to pero ChIP in either DMSO or 4OHT treatment condition.

Source: GEO: Gene Expression Omnibus - April 17, 2024 Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Homo sapiens Source Type: research