Ionic liquid-functionalized mesoporous multipod silica for simultaneously effective extraction of aflatoxin B < sub > 1 < /sub > and its two precursors from grain

In this study, a bisimidazolium-type ionic liquid functionalized mesoporous multipod silica (SiO2@mPMO-IL(im)2) was fabricated to extract AFB1 and its two precursors, i.e., averantin and sterigmatocystin. The SiO2@mPMO-IL(im)2 could simultaneously extract three targets with varied structures based on the multipods, mesopores, and multifunctional groups. The density functional theory calculations further verified the multiple interactions between SiO2@mPMO-IL(im)2 and targets. The fabricated SiO2@mPMO-IL(im)2 could effectively extract and determine three targets in grains by combing with dispersive solid-phase extraction and high-performance liquid chromatography. Good linearity (r2 > 0.9978), low LODs (0.9-1.5 μg kg-1) and LOQs (3.0-4.5 μg kg-1), satisfactory spiked recoveries (92.5%-106.8%) and high precisions (RSD<6.4%) were observed.SIGNIFICANCE AND NOVELTY: This work demonstrates the feasibility of SiO2@mPMO-IL(im)2 for simultaneous and effective extraction of toxins with varied structures and provides a promising sample preparation for the analysis of AFB1 and its precursors in grain samples.PMID:38609271 | DOI:10.1016/j.aca.2024.342544

Source: Analytica Chimica Acta - April 12, 2024 Category: Chemistry Authors: Xiaxing Feng Yaming Sun Tao Zhang Jingna Li Hailiang Zhao Wenjie Zhao Guoqiang Xiang Lijun He Source Type: research