Chronic sclerosing sialadenitis of the bilateral submandibular glands in childhood - a diagnostic dilemma

We present a case of CSS in a 5-year-old male child. He presented with bilateral submandibular swellings that clinically resembled discrete lumps, suspected to be tumors. The completely resected tumors composed predominantly of dense lymphoplasmacytic inflammatory infiltrate rich in IgG4-positive cells [77-90 IgG(+) cells per high-power field; IgG4(+)∕IgG(+) cells ratio of 42.77%]. We discuss the peculiarities of this case, and we also review the literature on CSS.PMID:38527991 | DOI:10.47162/RJME.65.1.14
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Authors: Source Type: research