Viruses, Vol. 16, Pages 622: Applying Next-Generation Sequencing to Track HIV-1 Drug Resistance Mutations Circulating in Portugal

Conclusions: We present the first evidence on TDR and ADR to INSTI regimens in followed up patients presenting for healthcare in Portugal. We observed low levels of TDR to INSTIs among ART-naïve and moderate levels in ART-exposed patients. Regimens containing PIs could be an alternative second line in patients with intermediate or high-level drug resistance, especially against second-generation INSTIs (dolutegravir, bictegravir, and cabotegravir).

Source: Viruses - April 17, 2024 Category: Virology Authors: Victor Pimentel Marta Pingarilho Cruz S. Sebasti ão Mafalda Miranda F átima Gonçalves Joaquim Cabanas In ês Costa Isabel Diogo Sandra Fernandes Olga Costa Rita Corte-Real M. Ros ário O. Martins Sofia G. Seabra Ana B. Abecasis Perp étua Gomes Tags: Article Source Type: research