Physiological role of NBCe2 in the regulation of electrolyte transport in the distal nephron.

Physiological role of NBCe2 in the regulation of electrolyte transport in the distal nephron. Am J Physiol Renal Physiol. 2015 Jul 1;:ajprenal.00192.2015 Authors: Wen D, Sansom SC Abstract The electrogenic Na+-HCO3- co-transporter 2 (NBCe2) is a newly discovered protein in the distal nephron. Our understanding is minimal regarding its physiological role in renal electrolyte transport. In this mini-review, we summarize the potential function of NBCe2 in the regulation of blood pressure, acid/base, and K+ and Ca2+ transport in the distal nephron. PMID: 26136555 [PubMed - as supplied by publisher]
Source: Am J Physiol Renal P... - Category: Urology & Nephrology Authors: Tags: Am J Physiol Renal Physiol Source Type: research