Rapid identifying of COX-2 inhibitors from turmeric (Curcuma longa) by bioaffinity ultrafiltration coupled with UPLC-Q Exactive-Orbitrap-MS and zebrafish-based in vivo validation

This study screened out and verified unreported COX-2 ligands, potentially accelerating the discovery of new bioactive compounds in other functional foods.PMID:38604020 | DOI:10.1016/j.bioorg.2024.107357

Source: Bioorganic Chemistry - April 11, 2024 Category: Chemistry Authors: Zhenwei Lan Rui Yang Hu Wang Xingyang Xue Yue Sun Shumei Wang Ying Zhang Jiang Meng Source Type: research