Perspective: The complex relationship between charge, mobility, and gas ‐phase protein structure

AbstractIon mobility spectrometry coupled to mass spectrometry (IMS/MS) is a widely used tool for biomolecular separations and structural elucidation. The application of IMS/MS has resulted in exciting developments in structural proteomics and genomics. This perspective gives a brief background of the field, addresses some of the important issues in making structural measurements, and introduces complementary techniques.

Source: Journal of Mass Spectrometry - April 12, 2024 Category: Chemistry Authors: Ian K. Webb Tags: PERSPECTIVE Source Type: research