Impact of metal coordination and pH on the antimicrobial activity of histatin 5 and the products of its hydrolysis

Dalton Trans., 2024, Advance Article DOI: 10.1039/D4DT00565A, PaperEmilia Dzie ń, Joanna Wątły, Arian Kola, Aleksandra Mikołajczyk, Adriana Miller, Agnieszka Matera-Witkiewicz, Daniela Valensin, Magdalena Rowińska-Żyrek The antimicrobial activity of histatin 5 and the products of its hydrolysis – its N-terminal fragment (histatin 5–8) and C-terminal one (histatin 8) and their metal complexes depends on pH. Zn(ii) coordination changes the structure of histatin 5–8 and increase its antimicrobial potency. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Dalton Trans. latest articles - April 12, 2024 Category: Chemistry Authors: Emilia Dzie ń Source Type: research