Evaluation of a hapten conjugate vaccine against the "zombie drug" xylazine

Chem Commun (Camb). 2024 Apr 10. doi: 10.1039/d4cc00883a. Online ahead of print.ABSTRACTXylazine has emerged as a primary adulterant in fentanyl, exacerbating the complexity of the opioid crisis. Yet, there is no approved drug that can reverse xylazine's pathophysiology. As a prelude to monoclonal antibodies being assessed as a viable therapeutic, a vaccine inquiry was conducted evaluating the immune response in reversing xylazine induced behavior effects.PMID:38596865 | DOI:10.1039/d4cc00883a

Source: Chemical Communications - April 10, 2024 Category: Chemistry Authors: Mingliang Lin Lisa M Eubanks Bin Zhou Kim D Janda Source Type: research