Pulse oximetry signal loss during hypoxic episodes in preterm infants receiving automated oxygen control

Conclusion: SL is common during pHE and must hence be considered in AOC-algorithm designs. Administering a “backup FiO2” (which reflects FiO2-requirements during normoxemia) during SL may prolong pHE with SL.  Trial registration: The study was registered atwww.clinicaltrials.gov under the registration no. NCT03785899.What is Known:• Previous studies examined SpO2 signal loss (SL) during routine manual oxygen control being rare, but pronounced in lower SpO2 states.• Oxygen titration during SL is unlikely to be beneficial as SpO2 may recover to a normoxic range.What is New:• Periods of low signal quality of SpO2 are common during pHEs and while supported with automated oxygen control (SPOC), FiO2 is set to a back-up value reflecting FiO2 requirements during normoxemia in response to SL, although SpO2 remained below target until signal recovery.• FiO2 overshoots following pHEs were rare during AOC and occurred with a delayed onset; therefore, increased FiO2 during SL does not necessarily lead to overshoots.

Source: European Journal of Pediatrics - April 9, 2024 Category: Pediatrics Source Type: research