Dynamic genomic changes in methotrexate-resistant human cancer cell lines beyond DHFR amplification suggest potential new targets for preventing drug resistance

British Journal of Cancer, Published online: 09 April 2024; doi:10.1038/s41416-024-02664-0Dynamic genomic changes in methotrexate-resistant human cancer cell lines beyond DHFR amplification suggest potential new targets for preventing drug resistance

Source: British Journal of Cancer - April 9, 2024 Category: Cancer & Oncology Authors: Xiang-Ning Meng Jin-Fa Ma Yang-He Liu Si-Qing Li Xu Wang Jing Zhu Meng-Di Cai Hui-Shu Zhang Tiantian Song Shukai Xing Li-Qing Hou Huan Guo Xiao-Bo Cui Jiang Han Peng Liu Guo-Hua Ji Wen-Jing Sun Jing-Cui Yu Song-Bin Fu Source Type: research