Construction of Thioglycoside Bond via asymmetric organocatalyzed sulfa-Michael/Aldol reaction: Access to 4 ’-thionucleosides

Chem. Commun., 2024, Accepted Manuscript DOI: 10.1039/D4CC00984C, CommunicationTao Wei, Ming-Sheng Xie, Hai-Ming Guo Thioglycoside bond formation via asymmetric sulfa-Michael/aldol reaction of (E)- β-nucleobase acrylketones and 1,4-dithiane-2,5-diol has been developed with a cinchona alkaloid-derived bifunctional squaramide chiral catalyst. Diverse purine, benzimidazole, and midazole are well... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Chem. Commun. latest articles - April 8, 2024 Category: Chemistry Authors: Tao Wei Source Type: research