EMC10 modulates hepatic ER stress and steatosis in an isoform specific manner

Endoplasmic reticulum (ER) membrane protein complex subunit 10 (EMC10) has been implicated in obesity. Here we investigated the roles of the two isoforms of EMC10, including a secreted isoform (scEMC10) and an ER membrane-bound isoform (mEMC10), in MASLD.

Source: Journal of Hepatology - April 7, 2024 Category: Gastroenterology Authors: Kuangyang Chen, Yahao Wang, Jia Yang, Nora Kl öting, Chuanfeng Liu, Jiarong Dai, Shuoshuo Jin, Lijiao Chen, Shan Liu, Yuzhao Liu, Yongzhuo Yu, Xiaoxia Liu, Qing Miao, Chong Wee Liew, Yangang Wang, Arne Dietrich, Matthias Blüher, Xuanchun Wang Tags: Research Article Source Type: research