Fetal facial profile markers of Down syndrome in the second and third trimesters of pregnancy

ConclusionsA small MNM angle and a positive FP line can be regarded as novel markers for Down syndrome. The FP line is an easy marker to measure, has a low FPR, does not require knowledge of normal reference values and has the potential to differentiate between Down syndrome and trisomy 18, as, in the latter, the FP line is often negative. Copyright © 2014 ISUOG. Published by John Wiley & Sons Ltd.
Source: Ultrasound in Obstetrics and Gynecology - Category: Radiology Authors: Tags: Original Paper Source Type: research