DPPA3 facilitates genome-wide DNA demethylation in mouse primordial germ cells

Genome-wide DNA demethylation occurs in mammalian primordial germ cells (PGCs) as part of the epigenetic reprogramming important for gametogenesis and resetting the epigenetic information for totipotency. Dppa3 (...

Source: BMC Genomics - April 5, 2024 Category: Genetics & Stem Cells Authors: Keisuke Toriyama, Wan Kin Au Yeung, Azusa Inoue, Kazuki Kurimoto, Yukihiro Yabuta, Mitinori Saitou, Toshinobu Nakamura, Toru Nakano and Hiroyuki Sasaki Tags: Research Source Type: research