Mutations in the leptin-melanocortin pathway and weight loss after bariatric surgery: a systematic review and meta-analysis

CONCLUSIONS: Mutations in leptin-melanocortin pathway genes reduce long-term weight loss after bariatric surgery, whereas this effect may not be reflected during the period of rapid weight loss within 12 months. These genetic variants increase the difficulties in maintaining patients' long-term weight loss.PMID:38577709 | DOI:10.1002/oby.24007

Source: Obesity - April 5, 2024 Category: Eating Disorders & Weight Management Authors: Nianrong Zhang Hao Wang Shuman Ran Zhe Wang Biao Zhou Siqi Wang Zhengqi Li Baoyin Liu Yuntao Nie Yishan Huang Hua Meng Source Type: research