Full-spectral genome analysis of natural killer/T cell lymphoma highlights impacts of genome instability in driving its progression

ConclusionsThe striking differences underlying the mutational landscapes between the primary and relapsed/refractory NKTCL patients highlight the importance of genomic instability in driving the progression of NKTCL. Our newly proposed molecular subtyping system is valuable in assisting patient stratification and novel treatment design towards a better prognosis in the age of precision medicine.
Source: Genome Medicine - Category: Genetics & Stem Cells Source Type: research