LAMP1 controls CXCL10-CXCR3 axis mediated inflammatory regulation of macrophage polarization during inflammatory stimulation

In conclusion, CXCL10-CXCR3 axis differentially directs macrophage polarization in inflammatory and non-inflammatory states, and autophagy protein LAMP1 acts as the switch controlling the direction of macrophage polarization by CXCL10-CXCR3.PMID:38555817 | DOI:10.1016/j.intimp.2024.111929

Source: International Immunopharmacology - March 31, 2024 Category: Allergy & Immunology Authors: Yingying Ye Lexing Li Hu Kang Ziyu Wan Mengjie Zhang Baocai Gang Jie Liu Guoquan Liu Wei Gu Source Type: research