Noninvasive fetal blood group antigen genotyping

Blood Transfus. 2024 Jan 29. doi: 10.2450/BloodTransfus.712. Online ahead of print.ABSTRACTNoninvasive fetal blood group antigen genotyping serves as a diagnostic tool to predict the risk of hemolytic disease of the fetus and newborn in pregnancies of immunized women. In addition, fetal RHD genotyping is used as an antenatal screening to guide targeted use of immunoglobulin prophylaxis in non-immunized RhD negative, pregnant women. Based on testing of cell-free DNA extracted from maternal plasma, these noninvasive assays demonstrate high performance accuracies. Consequently, noninvasive fetal blood group antigen genotyping has become standard care in transfusion medicine.PMID:38315532 | DOI:10.2450/BloodTransfus.712
Source: Blood Transfusion - Category: Hematology Authors: Source Type: research