Beyond Anatomy: Fat-Suppressed MR and Molecular Imaging of Spinal Pain Generators

Radiol Clin North Am. 2024 Mar;62(2):247-261. doi: 10.1016/j.rcl.2023.09.005. Epub 2023 Nov 13.ABSTRACTSpine pain is highly prevalent and costly, but evaluation with clinical features and anatomic imaging remain limited. Fat-suppressed MR imaging and molecular imaging (MI) may help identify inflammatory, lesional, and malignant causes. Numerous MI agents are available, each with advantages and disadvantages. Herein, FDG PET, prostate-specific membrane antigen (PSMA), bone radiotracers, and others are highlighted. No specific pain MI agents have been identified, but mechanisms of key agents are shown in video format, and the mechanism of PSMA as a theranostic agent is displayed. A multidisciplinary approach is needed to master this topic.PMID:38272618 | DOI:10.1016/j.rcl.2023.09.005
Source: Radiologic Clinics of North America - Category: Radiology Authors: Source Type: research