Common and Disparate Clinical Presentations and Mechanisms in Different Eosinophilic Gastrointestinal Diseases

Eosinophilic gastrointestinal diseases (EGIDs) are a group of diseases characterized by selective eosinophil infiltration of the gastrointestinal tract in the absence of other causes of eosinophilia. These diseases are generally driven by type 2 inflammation often in response to food allergen exposure. Common among all EGIDs is a clinical presentation characterized by a history of atopic disease with a variety of gastrointestinal symptoms. EGIDs are traditionally separated into eosinophilic esophagitis (EoE) and non-EoE EGIDs.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research