Delivering synaptic protein mRNAs via extracellular vesicles ameliorates cognitive impairment in a mouse model of Alzheimer ’s disease

Synaptic dysfunction with reduced synaptic protein levels is a core feature of Alzheimer ’s disease (AD). Synaptic proteins play a central role in memory processing, learning, and AD pathogenesis. Evidence sugg...

Source: BMC Medicine - March 25, 2024 Category: Internal Medicine Authors: Huimin Cai, Yana Pang, Ziye Ren, Xiaofeng Fu and Longfei Jia Tags: Research article Source Type: research