Angiomatosis prurigiforme: una nueva entidad propuesta para la proliferaci ón angiomatoide dérmica prominente subyacente a los cambios epidérmicos de prurigo nodularis/liquen simple crónico

Actas Dermosifiliogr. 2024 Mar 11:S0001-7310(24)00198-4. doi: 10.1016/j.ad.2024.03.010. Online ahead of print.ABSTRACTVascular hyperplasia is a common finding in prurigo nodularis/lichen simplex chronicus (LSC). The term prurigiform angiomatosis was recently proposed to describe a histologic pattern characterized by prominent vascular hyperplasia in patients with LSC. The aim of this study was to identify cases of LSC with this pattern and analyze associations with clinical and pathologic features and disease course. We reviewed 54 cases of histologically confirmed LSC and detected findings consistent with prurigiform angiomatosis in 10 (18.5%). The patients (7 men, 3 women) had a mean age of 59.7 years. The lesions were pruritic and predominantly located on the extremities and trunk. The most notable histologic finding was vascular proliferation in the superficial dermis associated with a lymphocytic inflammatory infiltrate. Recognition of prurigiform angiomatosis is important as it helps not only to distinguish LSC from other entities (mainly vascular tumors) but also to detect lesions that need to be surgically excised due to poor response to topical treatment.PMID:38479690 | DOI:10.1016/j.ad.2024.03.010

Source: Actas Dermo-Sifiliograficas - March 13, 2024 Category: Dermatology Authors: R Albero Gonz ález D Rizo Potau L Al ós Hernández P Castillo Fern ández A Garc ía Herrera Source Type: research