Enhanced reactivity of Li+@C60 toward thermal [2 + 2] cycloaddition by encapsulated Li+ Lewis acid

In this study, we report the synthesis of Li+@C60 derivatives via the thermal [2 + 2] cycloaddition reaction of styrene derivatives, achieving significantly higher yields of monofunctionalized Li+@C60 compared to previously reported reactions. Furthermore, by combining experimental and theoretical approaches, we clarified the range of applicable substrates for the thermal [2 + 2] cycloaddition of Li+@C60, highlighting the expanded scope of this straightforward and selective functionalization method.

Beilstein J. Org. Chem. 2024, 20, 653–660. doi:10.3762/bjoc.20.58

Source: Beilstein Journal of Organic Chemistry - March 25, 2024 Category: Chemistry Authors: Beilstein Journal of Organic Chemistry - Syndicated Feeds Tags: electron transfer fullerene ion-endohedral fullerene Lewis acid catalyst thermal [2 2] cycloaddition Full Research Paper Source Type: research