Evaluation of Pre-Analytical Variables for Human Papillomavirus Primary Screening from Self-Collected Vaginal Swabs

Human papillomavirus (HPV) primary screening is an effective approach to assessing cervical cancer risk. Self-collected vaginal swabs have shown promise to expand testing access, but there are limited data defining analytical performance criteria necessary for adoption of self-collected specimens, especially for those occurring outside the clinic, where the swab remains dry during transport. Here, we evaluated the performance of self-collected vaginal swabs for HPV detection using the Cobas 6800.

Source: Journal of Molecular Diagnostics - March 15, 2024 Category: Pathology Authors: Michelle Qi, Anissa R. Naranjo, Abigail J. Duque, Thomas S. Lorey, Jeffrey M. Schapiro, Betty J. Suh-Burgmann, Michael Rummel, Stephen J. Salipante, Nicolas Wentzensen, Dina N. Greene Tags: Regular article Source Type: research