Cancers, Vol. 16, Pages 1261: Predictors of Progression in a Series of 81 Adult Patients Surgically Managed for an Intracranial Hemangioblastoma: Implications for the Postoperative Follow-Up

Cancers, Vol. 16, Pages 1261: Predictors of Progression in a Series of 81 Adult Patients Surgically Managed for an Intracranial Hemangioblastoma: Implications for the Postoperative Follow-Up Cancers doi: 10.3390/cancers16071261 Authors: Elisabeth Garrido Huy Le Ngoc Jacques Guyotat Isabelle Pelissou-Guyotat Timothée Jacquesson Violaine Delabar Romain Manet Clémentine Gallet Tanguy Fenouil Nathalie Streichenberger Alexandre Vasiljevic David Meyronet Emmanuel Jouanneau François Ducray Chloe Dumot Thiebaud Picart The aim was to identify predictors of progression in a series of patients managed for an intracranial hemangioblastoma, in order to guide the postoperative follow-up modalities. The characteristics of 81 patients managed for an intracranial hemangioblastoma between January 2000 and October 2022 were retrospectively analyzed. The mean age at diagnosis was of 48 ± 16 years. Eleven (14%) patients had von Hippel–Lindau disease. The most frequent tumor location was the cerebellar hemispheres (n = 51, 65%) and 11 (14%) patients had multicentric hemangioblastomas. A gross total resection was achieved in 75 (93%) patients. Eighteen (22%) patients had a local progression, with a median progression-free survival of 56 months 95% CI [1; 240]. Eleven (14%) patients had a distant progression (new hemangioblastoma and/or growth of an already known hemangioblastoma). Local progression was more frequent in younger pa...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research